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  • Hot off the AAN Press: Fingolimod effective but safety an issue

    UPDATE 3-Novartis MS drug effective but safety an issue
    ZURICH, April 29 (Reuters) – Novartis AG  said 80-83 percent of those taking its multiple sclerosis drug FTY720 are relapse-free compared with 69 percent on the leading current treatment, but it reported a new patient death.
    Novartis said the patient died from aspiration pneumonia related to a [...]

  • Novartis MS drug linked to new side effect

    LONDON, April 14 — Fresh side-effect problems have emerged with Novartis AG’s experimental oral multiple sclerosis (MS) drug FTY720, with doctors reporting a case of haemorrhaging focal encephalitis.
    A case report on the patient who developed the condition after taking part in a Phase III clinical trial of the medicine — one of the big hopes [...]

  • The Age of Orals: Who Will Win the Race to the Market?

    Jan 23, 2009
    Oral Cladribine Reduces MS Relapses in Phase 3 Clinical Trial
    Oral cladribine (EMD Serono) reduced the relapse rate significantly more than inactive placebo in the phase 3 “CLARITY” study of 1,326 people with relapsing-remitting MS. These initial results – the first from any phase 3 study of oral therapy for MS — are reported [...]

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